Spengler redivivus? Garth Fowden’s First Millennium

The Millennium Run Observatory: First Light

Simulations of galaxy evolution aim to capture our current understanding as well as to make predictions for testing by future experiments. Simulations and observations are often compared in an indirect fashion: physical quantities are estimated from the observational data and compared to models. However, many applications can benefit from a more direct approach, where the observing process is a...

Thiourea-catalyzed enantioselective iso-Pictet-Spengler reactions.

A one-pot condensation of isotryptamines and aldehydes that affords enantiomerically enriched 4-substituted tetrahydro-γ-carbolines is reported. The reaction is induced by a chiral thiourea/benzoic acid dual catalyst system. Purification of the N-Boc-protected products by trituration or crystallization provides the optically pure tetrahydro-γ-carboline derivatives in a scalable and highly pract...

Artificial insemination redivivus: permutations within a penumbra.

The first influenza pandemic of the new millennium

In the spring of 2009, a novel influenza A virus of the H1N1 subtype emerged that transmitted efficiently among humans; by June of 2009, the outbreak reached pandemic status. The pandemic virus possesses six viral RNA segments from so-called triple reassortant swine viruses that emerged in North American pig populations in the late 1990s and two viral RNA segments from Eurasian avian-like swine...

Research Summary and Research Plan for Garth Isaak

This is a summary of research papers for the tenure packet of Garth Isaak. For this context I will write slightly diierently than a regular research summary. I will occasionally use the rst person. I will intentionally be somewhat informal, not deening terms or giving complete references, as they are contained in the papers. Instead, I will give a brief description and some of the context of th...